2025 MLB Wild Card Odds: Yankees, Cubs, Guardians Favored to Advance

Published October 02, 2025

The MLB postseason continues Thursday with the AL and NL wild-card series.

Which squads will come out on top and advance to the next round of the playoffs?

Here are the odds at DraftKings Sportsbook as of Oct. 2.

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AMERICAN LEAGUE

Detroit Tigers @ Cleveland Guardians
Tied 1-1

Game 3 Winner
Tigers: +105 underdog
Guardians: -127 favorite

Boston Red Sox @ New York Yankees
Tied 1-1

Game 3 Winner
Red Sox: +129 underdog
Yankees: -158 favorite

NATIONAL LEAGUE

San Diego Padres @ Chicago Cubs
Tied 1-1

Game 3 Winner
Padres: -105 underdog
Cubs: -115 favorite

Cincinnati Reds vs. Los Angeles Dodgers
LAD wins 2-0

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